Elizabeth recommends this excellent research article by Cort Johnson.
The immune system in chronic fatigue syndrome (ME/CFS) has been kind of like a mirage in the desert. Given the way the disease starts and its symptom presentation – so close to the “sickness behavior” produced during an infection – it seems that the immune system must be a major player in this illness.

Solid Ground at Last? Cytokines Make Good in Major ME/CFS Review